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J Clin Microbiol. 1975 February; 1(2): 201-205

Large-scale production of rubella precipitinogens and their use in the diagnostic laboratory.

R Cappel, A Schluederberg and D M Horstmann

ABSTRACT

A method for producing large quantities of rubella theta and iota precipitating antigens in Vero cells is described. Using this reagent, the detection of anti-theta antibodies was found to be as sensitive as the hemagglutination inhibition test for both the determination of immune status and the diagnosis of acute rubella infection. The detection of anti-iota antibodies may permit diagnosis of rubella infection, when the collection of the first serum has been delayed and the early rise of hemagglutin-inhibiting and anti-theta antibodies has been missed.

J Clin Microbiol. 1975 February; 1(2): 201-205






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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1975 by the American Society for Microbiology. All rights reserved.