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J Clin Microbiol. 1981 April; 13(4): 783-786

Detection of Yersinia enterocolitica heat-stable enterotoxin by suckling mouse bioassay.

M P Nunes and I D Ricciardi

ABSTRACT

A comparison of heat-stable enterotoxins from Escherichia coli and Yersinia enterocolitica by the suckling mouse bioassay showed that whereas E. coli heat-stable enterotoxin evoked a maximum ratio of gut weight to remaining body weight after a 4-h incubation period, the maximum ratio for Y. enterocolitica was achieved at 2 h, decreasing thereafter to values regarded as negative (less than 0.083). This action of Y. enterocolitica heat-stable enterotoxin may give false-negative results for the standard suckling mouse bioassay.


J Clin Microbiol. 1981 April; 13(4): 783-786







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