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J Clin Microbiol. 1982 June; 15(6): 1167-1168

Rapid detection in spinal fluid of beta-lactamase produced by ampicillin-resistant Haemophilus influenzae.

W H Boughton

ABSTRACT

The chromogenic cephalosporin nitrocefin was used to detect the presence of beta-lactamase in cerebrospinal fluid of patients suffering from ampicillin-resistant Haemophilus influenzae meningitis. Five samples of spinal fluid containing ampicillin-resistant isolates were studied, and all had beta-lactamase activity. When samples of spinal fluid containing 33 ampicillin-sensitive isolates and 234 sterile specimens were tested, no beta-lactamase activity was detected.

J Clin Microbiol. 1982 June; 15(6): 1167-1168






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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1982 by the American Society for Microbiology. All rights reserved.