This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Brown, A Articles by Garrity, G M Search for Related Content PubMed PubMed Citation Articles by Brown, A Articles by Garrity, G M

 Previous Article  |  Next Article 

J Clin Microbiol. 1982 August; 16(2): 230-235

Plasmid and surface antigen markers of endemic and epidemic Legionella pneumophila strains.

ABSTRACT

Environmental and clinical isolates of Legionella pneumophila obtained from the Pittsburgh Veterans Administration Medical Center were studied for the presence of plasmids and for unique surface antigens. The majority of environmental isolates contained a single 80-megadalton plasmid. After an epidemic of nosocomial Legionnaires disease subsided in the Spring of 1981, plasmid-bearing environmental isolates persisted in the environment. Whereas L. pneumophila could not be reisolated from most sites with plasmidless isolates. During this epidemic the attack rate was highest on wards with plasmidless isolates. All clinical isolates were plasmidless. Strains were serotyped by the indirect immunofluorescence method with serum from a single immunized rat which was used both without absorption and after absorption with various plasmid-bearing and plasmidless isolates. These studies suggested that a plasmid-associated surface antigen was present and that the most common plasmidless environmental serotype was similar to the epidemic clinical serotype.

This article has been cited by other articles:

• Doleans-Jordheim, A., Akermi, M., Ginevra, C., Cazalet, C., Kay, E., Schneider, D., Buchrieser, C., Atlan, D., Vandenesch, F., Etienne, J., Jarraud, S. (2006). Growth-phase-dependent mobility of the lvh-encoding region in Legionella pneumophila strain Paris. Microbiology 152: 3561-3568 [Abstract] [Full Text]  
• Huang, B., Yuan, Z., Heron, B. A., Gray, B. R., Eglezos, S., Bates, J. R., Savill, J. (2006). Distribution of 19 major virulence genes in Legionella pneumophila serogroup 1 isolates from patients and water in Queensland, Australia.. J Med Microbiol 55: 993-997 [Abstract] [Full Text]  
• Gaia, V., Fry, N. K., Harrison, T. G., Peduzzi, R. (2003). Sequence-Based Typing of Legionella pneumophila Serogroup 1 Offers the Potential for True Portability in Legionellosis Outbreak Investigation. J. Clin. Microbiol. 41: 2932-2939 [Abstract] [Full Text]