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J Clin Microbiol. 1982 November; 16(5): 953-956

Solid-phase radioimmunoassay for detection of plague antigen in animal tissue.

M E Soergel, F L Schaffer and H F Blank

ABSTRACT

A rapid and sensitive radioimmunoassay for the detection of soluble Yersinia pestis fraction I antigen using antibody-coated beads and radiolabeled immunoglobulin was applied to spleen-liver extracts, rendered noninfectious by either treatment or filtration, from rodents dead of plague. The procedure was capable of detecting nanogram amounts of soluble plague antigen.


J Clin Microbiol. 1982 November; 16(5): 953-956







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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1982 by the American Society for Microbiology. All rights reserved.