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J Clin Microbiol. 1983 February; 17(2): 374-376

Photodynamic inactivation of pseudorabies virus with methylene blue dye, light, and electricity.

J A Badylak, G Scherba and D P Gustafson

ABSTRACT

Pseudorabies virus was photoinactivated with a combination of methylene blue dye, light, and electricity. Viral suspensions were mixed with variable amounts of methylene blue dye and then were placed in a current source apparatus. Total inactivation of pseudorabies virus (1.7 X 10(6) 50% tissue culture infective doses per ml) was achieved with constant mixing, a methylene blue dye concentration of 10(-4) M, and an electrical current of 12 microA for 12 min.

J Clin Microbiol. 1983 February; 17(2): 374-376






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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1983 by the American Society for Microbiology. All rights reserved.