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J Clin Microbiol. 1983 October; 18(4): 994-995

Comparison of radioimmunoassay and fluorescent polarization immunoassay for quantitative determination of vancomycin concentrations in serum.

B H Ackerman, H G Berg, R G Strate and J C Rotschafer

ABSTRACT

A new fluorescent polarization immunoassay (Abbott Laboratories, Diagnostics Division, North Chicago, Ill.) was compared with a standard radioimmunoassay (American Diagnostics Corp., Newport Beach, Calif.) in 34 patients being treated with vancomycin. A total of 123 serum samples were divided and quantitatively analyzed for vancomycin by both assay methods. The results obtained indicated that the two assay methods are comparable (y = 1.01x - 0.81; r = 0.99).

J Clin Microbiol. 1983 October; 18(4): 994-995




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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1983 by the American Society for Microbiology. All rights reserved.