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J Clin Microbiol. 1975 September; 2(3): 218-221

Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis.

C R Sulzer, J W Glosser, F Rogers, W L Jones and M Frix

ABSTRACT

A presumptive hemagglutination test for the serological diagnosis of leptospirosis in humans is described. The antigen was prepared from a soluble alcohol extract of an andamana strain sorbed to human O-negative erythrocytes and preserved by pyruvic aldehyde fixation. In this study, the overall sensitivity of the hemagglutination test was 92% in contrast to 69% for the presumptive slide agglutination test. The specificity was 95% for the hemagglutination test in comparison with 83% for the slide test.

J Clin Microbiol. 1975 September; 2(3): 218-221




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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1975 by the American Society for Microbiology. All rights reserved.