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J Clin Microbiol. 1985 February; 21(2): 249-250

Radioenzymatic assay for trimethoprim in very small serum samples.

R Yogev, C Melick and L Tan-Pong

ABSTRACT

A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-microliter serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 microliters) can be achieved.

J Clin Microbiol. 1985 February; 21(2): 249-250






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