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J Clin Microbiol. 1985 September; 22(3): 462-464

Examination of the Rotazyme II enzyme immunoassay for the diagnosis of rotavirus gastroenteritis.

M Chernesky, S Castriciano, J Mahony and D DeLong

ABSTRACT

Rotazyme II, which is a shorter version of Rotazyme (less than 3 h), was compared with electron microscopy and Rotazyme for sensitivity and specificity on 229 human stool specimens. Compared with electron microscopy, the newer assay was found to be 99.4% sensitive and 97.3% specific for an overall agreement of 98.7%. After resolution of discordant results by blocking tests, the Rotazyme II enzyme immunoassay was shown to be more sensitive than electron microscopy and, therefore, 100% specific.


J Clin Microbiol. 1985 September; 22(3): 462-464




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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 1985 by the American Society for Microbiology. All rights reserved.