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J Clin Microbiol. 1987 February; 25(2): 305-308

Genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients.

D H Webb, A F Shields and K H Fife

ABSTRACT

We characterized the genomic variation of adenovirus type 5 isolates recovered from bone marrow transplant recipients in Seattle between 1976 and 1982. By restriction endonuclease analysis, we identified three new adenovirus genomic variants, each associated with a single invasive adenovirus infection. In addition, we were able to obtain suggestive evidence for a nosocomial spread of a particular group of isolates within this population. This study demonstrates that the technique of restriction endonuclease analysis is an important epidemiological tool for investigating viral infections.

J Clin Microbiol. 1987 February; 25(2): 305-308






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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1987 by the American Society for Microbiology. All rights reserved.