This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bergmann, O J Search for Related Content PubMed PubMed Citation Articles by Bergmann, O J

 Previous Article  |  Next Article 

J Clin Microbiol. 1988 October; 26(10): 2105-2109

Oral infections and septicemia in immunocompromised patients with hematologic malignancies.

University Department of Medicine and Hematology, Aarhus County Hospital, Denmark.

ABSTRACT

To estimate the role of oral infections during septicemic episodes in immunocompromised patients with hematologic malignancies, 78 febrile episodes in 46 patients were monitored with daily clinical and microbiological investigations. The 19 septicemic episodes did not differ from the 59 other febrile episodes in the qualitative composition of the aerobic and facultatively anaerobic oral microflora or in the presence of teeth or acute oral infections on day 1. The oral prevalence rates of members of the family Enterobacteriaceae were higher on days 10, 11, and 12 in the febrile episodes with septicemia when compared with those of febrile episodes without septicemia. The prevalence of a probable oral focus in septicemia was 10.5%, and the prevalence of a probable or possible oral origin in septicemia was 31.6%. The results suggest that prevention and elimination of oral infections may reduce the morbidity and perhaps even the mortality in these patients.

This article has been cited by other articles:

• SMITH, A.J., JACKSON, M.S., BAGG, J. (2001). The ecology of Staphylococcus species in the oral cavity. J Med Microbiol 50: 940-946 [Abstract] [Full Text]  
• Kostler, W. J., Hejna, M., Wenzel, C., Zielinski, C. C. (2001). Oral Mucositis Complicating Chemotherapy and/or Radiotherapy: Options for Prevention and Treatment. CA Cancer J Clin 51: 290-315 [Abstract] [Full Text]  
• Mosca, D. A., Hurst, M. A., So, W., Viajar, B. S. C., Fujii, C. A., Falla, T. J. (2000). IB-367, a Protegrin Peptide with In Vitro and In Vivo Activities against the Microflora Associated with Oral Mucositis. Antimicrob. Agents Chemother. 44: 1803-1808 [Abstract] [Full Text]  
• Bergmann, O. J, Ellermann-Eriksen, S., Mogensen, S. C, Ellegaard, J. (1995). Acyclovir given as prophylaxis against oral ulcers in acute myeloid leukaemia: randomised, double blind, placebo controlled trial. BMJ 310: 1169-1172 [Abstract] [Full Text]