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J Clin Microbiol. 1989 February; 27(2): 367-369

Rapid diagnosis of cytomegalovirus by indirect immunofluorescence assay with monoclonal antibody F6b in a commercially available kit.

G Lucas, J M Seigneurin, J Tamalet, S Michelson, M Baccard, J F Delagneau and P Deletoille

Diagnostics Pasteur, Marnes la Coquette, France.

ABSTRACT

Anti-human cytomegalovirus (CMV) monoclonal antibody (MAb) F6b produced by clone 95/12 was used for the rapid diagnosis (16 to 24 h) of CMV isolates in 308 clinical specimens and compared with classic isolation. MAb F6b gave 100% correlation with isolation. When this MAb was used for direct diagnosis with 212 urine and bronchoalveolar specimens, detection of CMV varied from 50 to 75% compared with viral isolation.

J Clin Microbiol. 1989 February; 27(2): 367-369






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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 1989 by the American Society for Microbiology. All rights reserved.