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J Clin Microbiol. 1990 July; 28(7): 1652-1654

Measurement of rotavirus-neutralizing coproantibody in children by fluorescent focus reduction assay.

B S Coulson and P J Masendycz

Department of Gastroenterology, Royal Children's Hospital, Parkville, Victoria, Australia.

ABSTRACT

A fluorescent focus reduction assay suitable for the measurement of rotavirus-neutralizing antibodies in the feces of children was developed. Of 408 stools tested, 7% showed false-positive neutralization, and the number of rotavirus serotypes neutralized by a fecal extract was proportional to the levels of antirotaviral immunoglobulin A in the extract.

J Clin Microbiol. 1990 July; 28(7): 1652-1654




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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1990 by the American Society for Microbiology. All rights reserved.