This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Sullender, W M Articles by Wertz, G W Search for Related Content PubMed PubMed Citation Articles by Sullender, W M Articles by Wertz, G W

Synthetic oligonucleotide probes differentiate respiratory syncytial virus subgroups in a nucleic acid hybridization assay.

Department of Pediatrics, University of Alabama, Birmingham School of Medicine 35294.

ABSTRACT

A new approach to respiratory syncytial virus subgroup differentiation has been developed on the basis of the hybridization of subgroup-specific synthetic oligonucleotides with viral mRNA. Two oligonucleotide probes were designed from the nucleotide sequences of an A and a B subgroup respiratory syncytial virus glycoprotein G gene. All 28 virus isolates tested were correctly classified by subgroup with these probes.

This article has been cited by other articles:

• Zlateva, K. T., Vijgen, L., Dekeersmaeker, N., Naranjo, C., Van Ranst, M. (2007). Subgroup Prevalence and Genotype Circulation Patterns of Human Respiratory Syncytial Virus in Belgium during Ten Successive Epidemic Seasons. J. Clin. Microbiol. 45: 3022-3030 [Abstract] [Full Text]  
• Zlateva, K. T., Lemey, P., Vandamme, A.-M., Van Ranst, M. (2004). Molecular Evolution and Circulation Patterns of Human Respiratory Syncytial Virus Subgroup A: Positively Selected Sites in the Attachment G Glycoprotein. J. Virol. 78: 4675-4683 [Abstract] [Full Text]  
• Sullender, W. M. (2000). Respiratory Syncytial Virus Genetic and Antigenic Diversity. Clin. Microbiol. Rev. 13: 1-15 [Abstract] [Full Text]