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J Clin Microbiol. 1976 May; 3(5): 513-518

Antibody response to Rocky Mountain spotted fever.

R H Kenyon, P G Canonico, L S Sammons, L R Bagley and C E Pedersen Jr

ABSTRACT

Various techniques were compared to determine the most sensitive method for detection of rocky Mountain spotted fever antibody. A radiometabolic technique for detection of Rocky Mountain spotted fever antibody is also described. In infected monkeys, the fluorescent antibody technique yielded the earliest evidence of seroconversion; with some monkeys the microagglutination procedure was equally effective. The fluorescent antibody and microagglutination measurements showed higher titers than those for complement fixation, Weil-Felix, or the radiometabolic techniques.

J Clin Microbiol. 1976 May; 3(5): 513-518




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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 1976 by the American Society for Microbiology. All rights reserved.