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J Clin Microbiol. 1992 February; 30(2): 517-519

Minimum number of pneumococci required for capsular antigen to be detectable by latex agglutination.

Regional Public Health Laboratory, University Hospital, Groningen, The Netherlands.

ABSTRACT

Forty-eight strains of Streptococcus pneumoniae were tested in vitro to determine the minimum number required for pneumococcal capsular antigen to be detectable by latex agglutination. It was found that 10(6) to 10(7) microorganisms per ml were needed and that antigen remained detectable even when viable pneumococci could no longer be demonstrated.

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