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J Clin Microbiol. 1993 January; 31(1): 138-141

Enzyme-linked immunosorbent assay for detection of human immunoglobulin G to lipopolysaccharide of spotted fever group rickettsiae.

D Jones, B Anderson, J Olson and C Greene

Viral and Rickettsial Zoonoses Branch, National Center for Infectious Diseases, Atlanta, Georgia 30333.

ABSTRACT

An enzyme-linked immunosorbent assay for detecting human immunoglobulin G to spotted fever group rickettsiae was developed and tested. The assay uses proteinase K-resistant material, characteristic of the rickettsial lipopolysaccharides shown to be group specific by immunoblots, as the antigen. The results indicate that the assay provides a sensitive, yet specific, alternative method for diagnosing rickettsial diseases.


J Clin Microbiol. 1993 January; 31(1): 138-141







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Copyright © 1993 by the American Society for Microbiology. All rights reserved.