This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Padhye, A A Articles by Peterson, S W Search for Related Content PubMed PubMed Citation Articles by Padhye, A A Articles by Peterson, S W

Osteomyelitis caused by Neosartorya pseudofischeri.

Emerging Bacterial and Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333.

ABSTRACT

The first case of osteomyelitis caused by Neosartorya pseudofischeri is reported. The patient, a 77-year-old male with a history of silicosis and tuberculosis, on X-ray examination revealed lytic lesions of L2 and L3 vertebrae suspicious for metastatic lesions. Histologic examination of biopsy specimens from vertebral bodies showed short, distorted, extra- and intracellular, hyaline hyphal fragments. The culture from the biopsy tissue produced numerous, evanescent asci containing eight ellipsoidal ascospores with two distinctive equatorial bands ca. 1 micron wide. When examined by a scanning electron microscope, ascospores exhibited a convex surface ornamented with raised flaps of tissue, in shape resembling triangular projections or long ridge lines. The conidial state (anamorph) was identified as Aspergillus thermomutatus on the basis of conidial columns which were smaller and less tightly packed as well as of a lighter shade of green than those observed in Aspergillus fumigatus. On the basis of the morphologic features of the ascospores, the teleomorph was identified as N. pseudofischeri.

This article has been cited by other articles:

• Balajee, S.A., Houbraken, J., Verweij, P.E., Hong, S-B., Yaghuchi, T., Varga, J., Samson, R.A. (2007). Aspergillus species identification in the clinical setting.. SIM 59: 39-46 [Abstract] [Full Text]  
• Samson, R.A., Hong, S., Peterson, S.W., Frisvad, J.C., Varga, J. (2007). Polyphasic taxonomy of Aspergillus section Fumigati and its teleomorph Neosartorya.. SIM 59: 147-203 [Abstract] [Full Text]  
• Balajee, S. A., Gribskov, J., Brandt, M., Ito, J., Fothergill, A., Marr, K. A. (2005). Mistaken Identity: Neosartorya pseudofischeri and Its Anamorph Masquerading as Aspergillus fumigatus. J. Clin. Microbiol. 43: 5996-5999 [Abstract] [Full Text]  
• Jarv, H., Lehtmaa, J., Summerbell, R. C., Hoekstra, E. S., Samson, R. A., Naaber, P. (2004). Isolation of Neosartorya pseudofischeri from Blood: First Hint of Pulmonary Aspergillosis. J. Clin. Microbiol. 42: 925-928 [Abstract] [Full Text]  
• Wang, L., Yokoyama, K., Miyaji, M., Nishimura, K. (2000). Mitochondrial Cytochrome b Gene Analysis of Aspergillus fumigatus and Related Species. J. Clin. Microbiol. 38: 1352-1358 [Abstract] [Full Text]  
• Cimerman, M., Gunde-Cimerman, N., Zalar, P., Perkovic, T. (1999). Femur Osteomyelitis Due to a Mixed Fungal Infection in a Previously Healthy Man. J. Clin. Microbiol. 37: 1532-1535 [Abstract] [Full Text]