This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Harasawa, R Articles by Tomiyama, T Search for Related Content PubMed PubMed Citation Articles by Harasawa, R Articles by Tomiyama, T

Evidence of pestivirus RNA in human virus vaccines.

Animal Center for Biomedical Research, Faculty of Medicine, University of Tokyo, Japan.

ABSTRACT

We examined live virus vaccines against measles, mumps, and rubella for the presence of pestivirus RNA or of pestiviruses by reverse transcription PCR. Pestivirus RNA was detected in two measles-mumps-rubella combined vaccines and in two monovalent vaccines against mumps and rubella. Nucleotide sequence analysis of the PCR products indicated that a modified live vaccine strain used for immunization of cattle against bovine viral diarrhea is not responsible for the contamination of the vaccines.

This article has been cited by other articles:

• Kojima, A., Yasuda, A., Asanuma, H., Ishikawa, T., Takamizawa, A., Yasui, K., Kurata, T. (2003). Stable High-Producer Cell Clone Expressing Virus-Like Particles of the Japanese Encephalitis Virus E Protein for a Second-Generation Subunit Vaccine. J. Virol. 77: 8745-8755 [Abstract] [Full Text]  
• Givens, M. D., Dykstra, C. C., Brock, K. V., Stringfellow, D. A., Kumar, A., Stephens, C. E., Goker, H., Boykin, D. W. (2003). Detection of Inhibition of Bovine Viral Diarrhea Virus by Aromatic Cationic Molecules. Antimicrob. Agents Chemother. 47: 2223-2230 [Abstract] [Full Text]  
• Vilcek, S., Paton, D. J., Minor, P., Bentley, M. (1999). No Confirmation of Pestivirus RNA in Human Virus Vaccines. J. Clin. Microbiol. 37: 1653-1653 [Full Text]