This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ravaggi, A Articles by Cariani, E Search for Related Content PubMed PubMed Citation Articles by Ravaggi, A Articles by Cariani, E

 Previous Article  |  Next Article 

J Clin Microbiol. 1994 September; 32(9): 2280-2284

Distribution of viral genotypes in Italy determined by hepatitis C virus typing by DNA immunoassay.

Institute of Chemistry, School of Medicine, University of Brescia, Italy.

ABSTRACT

The distribution of hepatitis C virus (HCV) genotypes in Italy was investigated by PCR amplification of the E1 region and hybridization with type I- and type II-specific nonisotopic probes. Positive PCR results were obtained for 65 of 72 patients (90.3%). Type I was detected in 13 of 72 patients (18%), type II was detected in 39 patients (54.2%), and a mixed type I-type II infection was detected in 7 patients (9.7%). Six amplification products not classified by this method shared a low level of homology with HCV types I and II. HCV type I was significantly associated with human immunodeficiency virus, whereas HCV type II was detected in older subjects who were negative for human immunodeficiency virus markers. These results indicate different epidemiological distributions of HCV types I and II in Italy.

This article has been cited by other articles:

• Rumi, M G, De Filippi, F, La Vecchia, C, Donato, M F, Gallus, S, Del Ninno, E, Colombo, M (2005). Hepatitis C reactivation in patients with chronic infection with genotypes 1b and 2c: a retrospective cohort study of 206 untreated patients. Gut 54: 402-406 [Abstract] [Full Text]  
• Muir, P., Kammerer, U., Korn, K., Mulders, M. N., Poyry, T., Weissbrich, B., Kandolf, R., Cleator, G. M., van Loon, A. M. (1998). Molecular Typing of Enteroviruses: Current Status and Future Requirements. Clin. Microbiol. Rev. 11: 202-227 [Abstract] [Full Text]  
• Rossi, G., Tucci, A., Cariani, E., Ravaggi, A., Rossini, A., Radaeli, E. (1997). Outbreak of Hepatitis C Virus Infection in Patients With Hematologic Disorders Treated With Intravenous Immunoglobulins: Different Prognosis According to the Immune Status. Blood 90: 1309-1314 [Abstract] [Full Text]