This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Andersen, B. M. Articles by Brenner, D. J. Search for Related Content PubMed PubMed Citation Articles by Andersen, B. M. Articles by Brenner, D. J.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, 01 1995, 76-78, Vol 33, No. 1
Copyright © 1995 by the American Society for Microbiology. All rights reserved.

Characterization of Neisseria elongata subsp. glycolytica isolates obtained from human wound specimens and blood cultures

BM Andersen, RS Weyant, AG Steigerwalt, CW Moss, DG Hollis, RE Weaver, D Ashford and DJ Brenner
Department of Medical Microbiology, University Hospital of Tromso, Norway.

Four slightly yellow-pigmented, alpha-hemolytic, gram-negative coccobacilli, three from wound specimens and one from multiple blood cultures of a patient with endocarditis, were identified as Neisseria elongata subsp. glycolytica on the basis of their overall biochemical and genetic similarities to this subspecies. These strains resembled N. elongata in their guanine-plus-cytosine contents (55.6 to 57.1 mol%) and in their overall cellular fatty acid profiles, which are characterized by large amounts of 16:0, 16:1 omega 7c, and 18:1 omega 7c fatty acids. Their identities were confirmed by species-level DNA relatedness (hydroxyapatite method) to the type strains of all three N. elongata subspecies. The biochemical profiles and cultural characteristics of these strains resembled those of the type strain of N. elongata subsp. glycolytica except for the production of a weak yellow growth pigment and alpha-hemolysis on sheep blood agar. They differed from N elongata subsp. elongata by the production of catalase, by the production of alpha-hemolysis on sheep blood agar, and by acid production from D-glucose. They differed from N. elongata subsp. nitroreducens by the production of catalase and an inability to reduce nitrate. These studies suggest a pathogenic potential for N. elongata subsp. glycolytica, usually considered to be a transient colonizer in humans.

This article has been cited by other articles:

• Hsiao, J.-F., Lee, M.-H., Chia, J.-H., Ho, W.-J., Chu, J.-J., Chu, P.-H. (2008). Neisseria elongata endocarditis complicated by brain embolism and abscess. J Med Microbiol 57: 376-381 [Abstract] [Full Text]  
• Evans, M., Yazdani, F., Malnick, H., Shah, J. J., Turner, D. P. J. (2007). Prosthetic valve endocarditis due to Neisseria elongata subsp. elongata in a patient with Klinefelter's syndrome. J Med Microbiol 56: 860-862 [Abstract] [Full Text]  
• Han, X. Y., Hong, T., Falsen, E. (2006). Neisseria bacilliformis sp. nov. Isolated from Human Infections. J. Clin. Microbiol. 44: 474-479 [Abstract] [Full Text]  
• Hombrouck-Alet, C., Poilane, I., Janoir-Jouveshomme, C., Fain, O., Cruaud, P., Thomas, M., Collignon, A. (2003). Utilization of 16S Ribosomal DNA Sequencing for Diagnosis of Septicemia Due to Neisseria elongata subsp. glycolytica in a Neutropenic Patient. J. Clin. Microbiol. 41: 3436-3437 [Abstract] [Full Text]