This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gonzalez, R.
Right arrow Articles by Perez-Schael, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gonzalez, R.
Right arrow Articles by Perez-Schael, I.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, 05 1997, 1103-1107, Vol 35, No. 5
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Age-specific prevalence of Escherichia coli with localized and aggregative adherence in Venezuelan infants with acute diarrhea

R Gonzalez, C Diaz, M Marino, R Cloralt, M Pequeneze and I Perez-Schael
Instituto de Biomedicina, Universidad Central de Venezuela, Ministerio de Sanidad y Asistencia Social, Caracas, Venezuela.

To evaluate the epidemiological significance of HEp-2 cell-adherent Escherichia coli isolates in diarrheal disease, we performed a study with 513 Venezuelan infants with diarrhea and 241 age-matched controls to determine the prevalence of enteropathogenic E. coli (enteroadherent E. coli, enterotoxigenic E. coli, enteroinvasive E. coli, and enterohemorrhagic E. coli) and their correlation with O:H serotypes. E. coli isolates exhibiting localized and aggregative adherence in the HEp- 2 cell assay were significantly more frequently isolated from the patients (8.5 and 26.9%, respectively) than from the controls (1.7 and 15%, respectively). This difference was significant for the group 0 to 2 months of age but for older infants. Regardless of age, E. coli isolates with diffuse adherence were found at similar frequencies in both the patients and the controls. A striking correlation between classic O serogroups and localized adherence was also observed. These findings confirm the pathogenic role of E. coli with localized and aggregative adherence in diarrheal disease, as well as the epidemiological importance of O:H serotyping for characterizing localized-adhering E. coli.


This article has been cited by other articles:

  • Weintraub, A. (2007). Enteroaggregative Escherichia coli: epidemiology, virulence and detection. J Med Microbiol 56: 4-8 [Abstract] [Full Text]  
  • Nguyen, T. V., Le Van, P., Le Huy, C., Gia, K. N., Weintraub, A. (2005). Detection and Characterization of Diarrheagenic Escherichia coli from Young Children in Hanoi, Vietnam. J. Clin. Microbiol. 43: 755-760 [Abstract] [Full Text]  
  • Pabst, W. L., Altwegg, M., Kind, C., Mirjanic, S., Hardegger, D., Nadal, D. (2003). Prevalence of Enteroaggregative Escherichia coli among Children with and without Diarrhea in Switzerland. J. Clin. Microbiol. 41: 2289-2293 [Abstract] [Full Text]  
  • Piva, I. C., Pereira, A. L., Ferraz, L. R., Silva, R. S. N., Vieira, A. C., Blanco, J. E., Blanco, M., Blanco, J., Giugliano, L. G. (2003). Virulence Markers of Enteroaggregative Escherichia coli Isolated from Children and Adults with Diarrhea in Brasilia, Brazil. J. Clin. Microbiol. 41: 1827-1832 [Abstract] [Full Text]  
  • Scaletsky, I. C. A., Pedroso, M. Z., Oliva, C. A. G., Carvalho, R. L. B., Morais, M. B., Fagundes-Neto, U. (1999). A Localized Adherence-Like Pattern as a Second Pattern of Adherence of Classic Enteropathogenic Escherichia coli to HEp-2 Cells That Is Associated with Infantile Diarrhea. Infect. Immun. 67: 3410-3415 [Abstract] [Full Text]  
  • Gomes, T. A. T., Vieira, M. A. M., Abe, C. M., Rodrigues, D., Griffin, P. M., Ramos, S. R. T. S. (1998). Adherence Patterns and Adherence-Related DNA Sequences in Escherichia coli Isolates from Children with and without Diarrhea in Sao Paulo City, Brazil. J. Clin. Microbiol. 36: 3609-3613 [Abstract] [Full Text]  
  • Yamashiro, T., Nakasone, N., Higa, N., Iwanaga, M., Insisiengmay, S., Phounane, T., Munnalath, K., Sithivong, N., Sisavath, L., Phanthauamath, B., Chomlasak, K., Sisulath, P., Vongsanith, P. (1998). Etiological Study of Diarrheal Patients in Vientiane, Lao People's Democratic Republic. J. Clin. Microbiol. 36: 2195-2199 [Abstract] [Full Text]  
  • Nataro, J. P., Kaper, J. B. (1998). Diarrheagenic Escherichia coli. Clin. Microbiol. Rev. 11: 142-201 [Abstract] [Full Text]  
  • Perez-Schael, I., Guntinas, M. J., Perez, M., Pagone, V., Rojas, A. M., Gonzalez, R., Cunto, W., Hoshino, Y., Kapikian, A. Z. (1997). Efficacy of the Rhesus Rotavirus-Based Quadrivalent Vaccine in Infants and Young Children in Venezuela. NEJM 337: 1181-1187 [Abstract] [Full Text]