This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Abele-Horn, M. Articles by Zimmermann, A. Search for Related Content PubMed PubMed Citation Articles by Abele-Horn, M. Articles by Zimmermann, A.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, 05 1997, 1199-1202, Vol 35, No. 5
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Association of Ureaplasma urealyticum biovars with clinical outcome for neonates, obstetric patients, and gynecological patients with pelvic inflammatory disease

M Abele-Horn, C Wolff, P Dressel, F Pfaff and A Zimmermann
Max von Pettenkofer Institute, Ludwig Maximilian University, Munich, Germany.

In this prospective study, the prevalence of the two Ureaplasma urealyticum biovars, parvo and T960, was determined in pregnant women and in gynecological patients colonized by ureaplasmas. Furthermore, we investigated the association of these biovars with gynecological complications and adverse pregnancy outcome. Isolates of U. urealyticum from 254 women were biotyped by a PCR method recently developed. The parvo biovar was found in 81% (206 of 254) of the patients, and the T960 biovar was found in 30% (76 of 254) of the patients; 6% (14 of 254) of the women were coinfected. Identical biovars were detected in mothers and their infants. Serial isolations or cultures from different sampling sites of the same individual revealed the same biovar. T960 was dominant in patients with pelvic inflammatory disease (57%) and patients who had had a miscarriage (42%), showed a higher rate of tetracycline resistance than did parvo isolates (55 versus 18%), and seemed to have more adverse effects on pregnancy outcome with regard to birth weight (2,500 versus 1,720 g), gestational age (35 versus 30 weeks), and preterm delivery (35 versus 77%).

This article has been cited by other articles:

• Vancutsem, E., Echahidi, F., Van Geel, K., Muyldermans, G., Soetens, O., Naessens, A. (2008). Production of Recombinant Antigens of Ureaplasma parvum Serotypes 3 and 6 for Development of a Serological Assay. CVI 15: 447-451 [Abstract] [Full Text]  
• Kataoka, S., Yamada, T., Chou, K., Nishida, R., Morikawa, M., Minami, M., Yamada, H., Sakuragi, N., Minakami, H. (2006). Association between Preterm Birth and Vaginal Colonization by Mycoplasmas in Early Pregnancy. J. Clin. Microbiol. 44: 51-55 [Abstract] [Full Text]  
• Waites, K. B., Katz, B., Schelonka, R. L. (2005). Mycoplasmas and Ureaplasmas as Neonatal Pathogens. Clin. Microbiol. Rev. 18: 757-789 [Abstract] [Full Text]  
• Katz, B., Patel, P., Duffy, L., Schelonka, R. L., Dimmitt, R. A., Waites, K. B. (2005). Characterization of Ureaplasmas Isolated from Preterm Infants with and without Bronchopulmonary Dysplasia. J. Clin. Microbiol. 43: 4852-4854 [Abstract] [Full Text]  
• Stellrecht, K. A., Woron, A. M., Mishrik, N. G., Venezia, R. A. (2004). Comparison of Multiplex PCR Assay with Culture for Detection of Genital Mycoplasmas. J. Clin. Microbiol. 42: 1528-1533 [Abstract] [Full Text]  
• Bebear, C. M., Renaudin, H., Charron, A., Clerc, M., Pereyre, S., Bebear, C. (2003). DNA Gyrase and Topoisomerase IV Mutations in Clinical Isolates of Ureaplasma spp. and Mycoplasma hominis Resistant to Fluoroquinolones. Antimicrob. Agents Chemother. 47: 3323-3325 [Abstract] [Full Text]  
• Viscardi, R. M., Kaplan, J., Lovchik, J. C., He, J. R., Hester, L., Rao, S., Hasday, J. D. (2002). Characterization of a Murine Model of Ureaplasma urealyticum Pneumonia. Infect. Immun. 70: 5721-5729 [Abstract] [Full Text]  
• Yoshida, T., Maeda, S.-I., Deguchi, T., Ishiko, H. (2002). Phylogeny-Based Rapid Identification of Mycoplasmas and Ureaplasmas from Urethritis Patients. J. Clin. Microbiol. 40: 105-110 [Abstract] [Full Text]  
• Pitcher, D., Sillis, M., Robertson, J. A. (2001). Simple Method for Determining Biovar and Serovar Types of Ureaplasma urealyticum Clinical Isolates Using PCR-Single-Strand Conformation Polymorphism Analysis. J. Clin. Microbiol. 39: 1840-1844 [Abstract] [Full Text]  
• Kong, F., Ma, Z., James, G., Gordon, S., Gilbert, G. L. (2000). Species Identification and Subtyping of Ureaplasma parvum and Ureaplasma urealyticum Using PCR-Based Assays. J. Clin. Microbiol. 38: 1175-1179 [Abstract] [Full Text]  
• Kong, F., Zhu, X., Wang, W., Zhou, X., Gordon, S., Gilbert, G. L. (1999). Comparative Analysis and Serovar-Specific Identification of Multiple-Banded Antigen Genes of Ureaplasma urealyticum Biovar 1. J. Clin. Microbiol. 37: 538-543 [Abstract] [Full Text]  
• Knox, C. L., Timms, P. (1998). Comparison of PCR, Nested PCR, and Random Amplified Polymorphic DNA PCR for Detection and Typing of Ureaplasma urealyticum in Specimens from Pregnant Women. J. Clin. Microbiol. 36: 3032-3039 [Abstract] [Full Text]