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Journal of Clinical Microbiology, May 1997, 1255-1257, Vol 35, No. 5
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Persistent JC virus (JCV) infection is demonstrated by continuous shedding of the same JCV strains

T Kitamura, C Sugimoto, A Kato, H Ebihara, M Suzuki, F Taguchi, K Kawabe and Y Yogo
Department of Urology, Branch Hospital, Faculty of Medicine, University of Tokyo, Japan.

The polyomavirus JC virus (JCV), the causative agent of progressive multifocal leukoencephalopathy, is ubiquitous in the human population, infecting children asymptomatically. JCV is often detected in normal renal tissue and in the urine of healthy individuals. We demonstrate that renal JCV represents that which persists after primary infection.

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