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Journal of Clinical Microbiology, Jul 1997, 1791-1793, Vol 35, No. 7
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Detection of rhinovirus in sinus brushings of patients with acute community-acquired sinusitis by reverse transcription-PCR

A Pitkaranta, E Arruda, H Malmberg and FG Hayden
Department of Internal Medicine, University of Virginia, Charlottesville 22908, USA.

Of 20 adults with acute community-acquired sinusitis (ACAS), rhinovirus was detected in specimens from 10 (50%) patients, including maxillary aspirates from 8 (40%) patients and nasal swabs from 9 (45%) patients, by reverse transcription-PCR (RT-PCR). Human coronavirus was detected by RT-PCR in nasal swabs from 3 of 20 patients but in no sinus secretions. These findings suggest that rhinovirus is an important cause of ACAS and that viral invasion of the sinus cavity itself may be a common event during the disease.

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