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Journal of Clinical Microbiology, March 1998, p. 840-842, Vol. 36, No. 3
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Enteroaggregative, Shiga Toxin-Producing Escherichia coli O111:H2 Associated with an Outbreak of Hemolytic-Uremic Syndrome

Stefano Morabito,1 Helge Karch,2 Patrizia Mariani-Kurkdjian,3 Herbert Schmidt,2 Fabio Minelli,1 Edouard Bingen,3 and Alfredo Caprioli1,*

Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Rome, Italy1; Institut für Hygiene und Mikrobiologie, Universität Würzburg, Würzburg, Germany2; and Service de Microbiologie, Hôpital Robert Debré, Paris, France3

Received 11 August 1997/Returned for modification 24 September 1997/Accepted 1 December 1997

Shiga toxin-producing Escherichia coli O111:H2 strains from an outbreak of hemolytic-uremic syndrome showed aggregative adhesion to HEp-2 cells and harbored large plasmids which hybridized with the enteroaggregative E. coli probe PCVD432. These strains present a novel combination of virulence factors and might be as pathogenic to humans as the classic enterohemorrhagic E. coli.


* Corresponding author. Mailing address: Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy. Phone: 396 49902727. Fax: 396 49387077. E-mail: a.caprio{at}iss.it.


Journal of Clinical Microbiology, March 1998, p. 840-842, Vol. 36, No. 3
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.



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