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Journal of Clinical Microbiology, March 1998, p. 840-842, Vol. 36, No. 3
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
Enteroaggregative, Shiga Toxin-Producing
Escherichia coli O111:H2 Associated with an Outbreak of
Hemolytic-Uremic Syndrome
Stefano
Morabito,1
Helge
Karch,2
Patrizia
Mariani-Kurkdjian,3
Herbert
Schmidt,2
Fabio
Minelli,1
Edouard
Bingen,3 and
Alfredo
Caprioli1,*
Laboratorio di Medicina Veterinaria, Istituto
Superiore di Sanità, Rome, Italy1;
Institut für Hygiene und Mikrobiologie, Universität
Würzburg, Würzburg, Germany2; and
Service de Microbiologie, Hôpital Robert Debré,
Paris, France3
Received 11 August 1997/Returned for modification 24 September
1997/Accepted 1 December 1997
Shiga toxin-producing Escherichia coli O111:H2 strains
from an outbreak of hemolytic-uremic syndrome showed aggregative
adhesion to HEp-2 cells and harbored large plasmids which hybridized
with the enteroaggregative E. coli probe PCVD432. These
strains present a novel combination of virulence factors and might be
as pathogenic to humans as the classic enterohemorrhagic E. coli.
*
Corresponding author. Mailing address: Laboratorio di
Medicina Veterinaria, Istituto Superiore di Sanità, Viale Regina
Elena 299, 00161 Rome, Italy. Phone: 396 49902727. Fax: 396 49387077. E-mail: a.caprio{at}iss.it.
Journal of Clinical Microbiology, March 1998, p. 840-842, Vol. 36, No. 3
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
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