This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bonnet, R.
Right arrow Articles by Forestier, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bonnet, R.
Right arrow Articles by Forestier, C.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, June 1998, p. 1777-1780, Vol. 36, No. 6
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Non-O157:H7 Stx2-Producing Escherichia coli Strains Associated with Sporadic Cases of Hemolytic-Uremic Syndrome in Adults

R. Bonnet,1 B. Souweine,2 G. Gauthier,3 C. Rich,1 V. Livrelli,1 J. Sirot,1 B. Joly,1 and C. Forestier1,*

Laboratoire de Bactériologie, Faculté de Médecine-Pharmacie, Université d'Auvergne-Clermont-1,1 Service de Réanimation-Néphrologie, Centre Hospitalier Régional Universitaire,2 and Société Genolife, Biopôle Clermont-Limagne,3 Clermont-Ferrand, France

Received 2 December 1997/Returned for modification 17 February 1998/Accepted 17 March 1998

From August 1996 to May 1997, six verotoxin-producing Escherichia coli (VTEC) strains were isolated from stool specimens of adults suffering from hemolytic-uremic syndrome (HUS). All the isolates were stx2 positive and belonged to different serotypes: O6:H4, O91:H10, O91:H21, O rough:H16, OX3:H-, and O nontypeable:H-. The enterohemolysin (Ehly)-encoding genes were detected in two isolates, and none of the isolates harbors the intimin (Eae)-encoding gene. These findings suggest that stx2-positive non-O157:H7 VTEC is a major cause of HUS in adults and that several sources of pathogens are responsible for local endemic infections.

* Corresponding author. Mailing address: Laboratoire de Bactériologie, Faculté de Pharmacie, Université d'Auvergne, 28, place H. Dunant, 63001 Clermont-Ferrand, France. Phone: (33) 4 73 60 80 19. Fax: (33) 4 73 27 74 94. E-mail: Christiane.forestier{at}u-clermont1.fr.

Journal of Clinical Microbiology, June 1998, p. 1777-1780, Vol. 36, No. 6
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Bielaszewska, M., Stoewe, F., Fruth, A., Zhang, W., Prager, R., Brockmeyer, J., Mellmann, A., Karch, H., Friedrich, A. W. (2009). Shiga Toxin, Cytolethal Distending Toxin, and Hemolysin Repertoires in Clinical Escherichia coli O91 Isolates. J. Clin. Microbiol. 47: 2061-2066 [Abstract] [Full Text]  
  • Grys, T. E., Sloan, L. M., Rosenblatt, J. E., Patel, R. (2009). Rapid and Sensitive Detection of Shiga Toxin-Producing Escherichia coli from Nonenriched Stool Specimens by Real-Time PCR in Comparison to Enzyme Immunoassay and Culture. J. Clin. Microbiol. 47: 2008-2012 [Abstract] [Full Text]  
  • Girardeau, J. P., Bertin, Y., Martin, C. (2009). Genomic analysis of the PAI ICL3 locus in pathogenic LEE-negative Shiga toxin-producing Escherichia coli and Citrobacter rodentium. Microbiology 155: 1016-1027 [Abstract] [Full Text]  
  • Stephan, R., Schumacher, S., Corti, S., Krause, G., Danuser, J., Beutin, L. (2008). Prevalence and Characteristics of Shiga Toxin-Producing Escherichia coli in Swiss Raw Milk Cheeses Collected at Producer Level. J DAIRY SCI 91: 2561-2565 [Abstract] [Full Text]  
  • Tarr, C. L., Nelson, A. M., Beutin, L., Olsen, K. E. P., Whittam, T. S. (2008). Molecular Characterization Reveals Similar Virulence Gene Content in Unrelated Clonal Groups of Escherichia coli of Serogroup O174 (OX3). J. Bacteriol. 190: 1344-1349 [Abstract] [Full Text]  
  • Beutin, L., Miko, A., Krause, G., Pries, K., Haby, S., Steege, K., Albrecht, N. (2007). Identification of Human-Pathogenic Strains of Shiga Toxin-Producing Escherichia coli from Food by a Combination of Serotyping and Molecular Typing of Shiga Toxin Genes. Appl. Environ. Microbiol. 73: 4769-4775 [Abstract] [Full Text]  
  • Talukder, K. A., Mondol, A. S., Islam, M. A., Islam, Z., Dutta, D. K., Khajanchi, B. K., Azmi, I. J., Hossain, M. A., Rahman, M., Cheasty, T., Cravioto, A., Nair, G. B., Sack, D. A. (2007). A novel serovar of Shigella dysenteriae from patients with diarrhoea in Bangladesh. J Med Microbiol 56: 654-658 [Abstract] [Full Text]  
  • Vali, L., Hamouda, A., Hoyle, D. V., Pearce, M. C., Whitaker, L. H. R., Jenkins, C., Knight, H. I., Smith, A. W., Amyes, S. G. B. (2007). Antibiotic resistance and molecular epidemiology of Escherichia coli O26, O103 and O145 shed by two cohorts of Scottish beef cattle. J Antimicrob Chemother 59: 403-410 [Abstract] [Full Text]  
  • Hussein, H. S. (2007). Prevalence and pathogenicity of Shiga toxin-producing Escherichia coli in beef cattle and their products. J ANIM SCI 85: E63-E72 [Abstract] [Full Text]  
  • Luck, S. N., Badea, L., Bennett-Wood, V., Robins-Browne, R., Hartland, E. L. (2006). Contribution of FliC to Epithelial Cell Invasion by Enterohemorrhagic Escherichia coli O113:H21. Infect. Immun. 74: 6999-7004 [Abstract] [Full Text]  
  • Vaz, T. M. I., Irino, K., Nishimura, L. S., Cergole-Novella, M. C., Guth, B. E. C. (2006). Genetic Heterogeneity of Shiga Toxin-Producing Escherichia coli Strains Isolated in Sao Paulo, Brazil, from 1976 through 2003, as Revealed by Pulsed-Field Gel Electrophoresis.. J. Clin. Microbiol. 44: 798-804 [Abstract] [Full Text]  
  • Wang, J.-Y., Wang, S.-S., Yin, P.-Z. (2006). Haemolytic-uraemic syndrome caused by a non-O157 : H7 Escherichia coli strain in experimentally inoculated dogs. J Med Microbiol 55: 23-29 [Abstract] [Full Text]  
  • Girardeau, J. P., Dalmasso, A., Bertin, Y., Ducrot, C., Bord, S., Livrelli, V., Vernozy-Rozand, C., Martin, C. (2005). Association of Virulence Genotype with Phylogenetic Background in Comparison to Different Seropathotypes of Shiga Toxin-Producing Escherichia coli Isolates. J. Clin. Microbiol. 43: 6098-6107 [Abstract] [Full Text]  
  • Luck, S. N., Bennett-Wood, V., Poon, R., Robins-Browne, R. M., Hartland, E. L. (2005). Invasion of Epithelial Cells by Locus of Enterocyte Effacement-Negative Enterohemorrhagic Escherichia coli. Infect. Immun. 73: 3063-3071 [Abstract] [Full Text]  
  • Maldonado, Y., Fiser, J. C., Nakatsu, C. H., Bhunia, A. K. (2005). Cytotoxicity Potential and Genotypic Characterization of Escherichia coli Isolates from Environmental and Food Sources. Appl. Environ. Microbiol. 71: 1890-1898 [Abstract] [Full Text]  
  • Fratamico, P. M., Bagi, L. K., Bush, E. J., Solow, B. T. (2004). Prevalence and Characterization of Shiga Toxin-Producing Escherichia coli in Swine Feces Recovered in the National Animal Health Monitoring System's Swine 2000 Study. Appl. Environ. Microbiol. 70: 7173-7178 [Abstract] [Full Text]  
  • Tzipori, S., Sheoran, A., Akiyoshi, D., Donohue-Rolfe, A., Trachtman, H. (2004). Antibody Therapy in the Management of Shiga Toxin-Induced Hemolytic Uremic Syndrome. Clin. Microbiol. Rev. 17: 926-941 [Abstract] [Full Text]  
  • Beutin, L., Krause, G., Zimmermann, S., Kaulfuss, S., Gleier, K. (2004). Characterization of Shiga Toxin-Producing Escherichia coli Strains Isolated from Human Patients in Germany over a 3-Year Period. J. Clin. Microbiol. 42: 1099-1108 [Abstract] [Full Text]  
  • Jenkins, C., Willshaw, G. A., Evans, J., Cheasty, T., Chart, H., Shaw, D. J., Dougan, G., Frankel, G., Smith, H. R. (2003). Subtyping of virulence genes in verocytotoxin-producing Escherichia coli (VTEC) other than serogroup O157 associated with disease in the United Kingdom. J Med Microbiol 52: 941-947 [Abstract] [Full Text]  
  • Bettelheim, K. A. (2003). Non-O157 Verotoxin-Producing Escherichia coli: A Problem, Paradox, and Paradigm. Exp. Biol. Med. 228: 333-344 [Abstract] [Full Text]  
  • Hussein, H. S., Thran, B. H., Hall, M. R., Kvasnicka, W. G., Torell, R. C. (2003). Verotoxin-Producing Escherichia coli in Culled Beef Cows Grazing Rangeland Forages. Exp. Biol. Med. 228: 352-357 [Abstract] [Full Text]  
  • Arthur, T. M., Barkocy-Gallagher, G. A., Rivera-Betancourt, M., Koohmaraie, M. (2002). Prevalence and Characterization of Non-O157 Shiga Toxin-Producing Escherichia coli on Carcasses in Commercial Beef Cattle Processing Plants. Appl. Environ. Microbiol. 68: 4847-4852 [Abstract] [Full Text]  
  • Pradel, N., Leroy-Setrin, S., Joly, B., Livrelli, V. (2002). Genomic Subtraction To Identify and Characterize Sequences of Shiga Toxin-Producing Escherichia coli O91:H21. Appl. Environ. Microbiol. 68: 2316-2325 [Abstract] [Full Text]  
  • Schmidt, H., Zhang, W.-L., Hemmrich, U., Jelacic, S., Brunder, W., Tarr, P. I., Dobrindt, U., Hacker, J., Karch, H. (2001). Identification and Characterization of a Novel Genomic Island Integrated at selC in Locus of Enterocyte Effacement-Negative, Shiga Toxin-Producing Escherichia coli. Infect. Immun. 69: 6863-6873 [Abstract] [Full Text]  
  • Hurley, B. P., Thorpe, C. M., Acheson, D. W. K. (2001). Shiga Toxin Translocation across Intestinal Epithelial Cells Is Enhanced by Neutrophil Transmigration. Infect. Immun. 69: 6148-6155 [Abstract] [Full Text]  
  • Pradel, N., Boukhors, K., Bertin, Y., Forestier, C., Martin, C., Livrelli, V. (2001). Heterogeneity of Shiga Toxin-Producing Escherichia coli Strains Isolated from Hemolytic-Uremic Syndrome Patients, Cattle, and Food Samples in Central France. Appl. Environ. Microbiol. 67: 2460-2468 [Abstract] [Full Text]  
  • Pradel, N., Livrelli, V., De Champs, C., Palcoux, J.-B., Reynaud, A., Scheutz, F., Sirot, J., Joly, B., Forestier, C. (2000). Prevalence and Characterization of Shiga Toxin-Producing Escherichia coli Isolated from Cattle, Food, and Children during a One-Year Prospective Study in France. J. Clin. Microbiol. 38: 1023-1031 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»