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Journal of Clinical Microbiology, July 1998, p. 2115-2116, Vol. 36, No. 7
Centers for Disease Control and Prevention,
Public Health Service, U.S. Department of Health and Human Services,
Atlanta, Georgia 30333
Received 22 December 1997/Returned for modification 8 February
1998/Accepted 15 April 1998
Until recently, group B streptococcus, serotype V (GBS-V), was an
infrequent cause of disease. It is now recognized as a significant cause of infections in both children and adults. To determine if this
increase was due to the recent introduction and spread of a single
clone of GBS-V, we analyzed, by pulsed-field gel electrophoresis (PFGE), the SmaI chromosomal DNA digests of 45 bacteria: 41 isolated from human infections between 1986 and 1996 in the United
States, 2 from human infections in Argentina, and 2 from naturally
infected mice. Seventeen patterns were found and arbitrarily designated patterns A to Q. Pattern N constituted 24 (53%) of the isolates and
was found in all of the years tested and from all surveillance areas,
as well as in both isolates from Argentina, and was very similar to the
GBS-V isolated from a mouse. Pattern P was found in three isolates,
pattern F was found in two, and the remaining patterns were found in
one isolate each. We concluded that the majority of isolates of GBS-V
are of one PFGE subtype and that this subtype was predominate before
the increase in disease caused by GBS-V and that GBS-V disease is
caused by several different subtypes.
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
Sudden Increase in Isolation of Group B
Streptococci, Serotype V, Is Not Due to Emergence of a New Pulsed-Field
Gel Electrophoresis Type
*
Corresponding author. Mailing address: Centers for
Disease Control and Prevention, Atlanta, GA 30333. Phone: (404)
639-2417. Fax: (404) 639-3123. E-mail: jae1{at}cdc.gov.
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