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Journal of Clinical Microbiology, July 1998, p. 2131-2134, Vol. 36, No. 7
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Experimental Transmission of Ehrlichia equi to Horses through Naturally Infected Ticks (Ixodes pacificus) from Northern California

Gerhard H. Reubel,1,* Robert B. Kimsey,2 Jeffrey E. Barlough,1 and John E. Madigan1

Department of Medicine and Epidemiology, School of Veterinary Medicine,1 and Department of Entomology, College of Agriculture,2 University of California, Davis, California 95616

Received 2 December 1997/Returned for modification 24 February 1998/Accepted 7 April 1998

We report the experimental transmission of Ehrlichia equi from naturally infected Ixodes pacificus ticks to horses. Three weeks after exposure to ticks, two of three horses developed clinical signs compatible with E. equi infection, while one horse remained asymptomatic. 16S rRNA gene PCR of blood leukocyte lysates was positive for all horses at various time points; two horses seroconverted. The 16S rRNA gene sequences amplified from tick-exposed horses showed more than 99% homology to corresponding fragments of the 16S rRNA genes of E. equi, Ehrlichia phagocytophila, and the human granulocytic ehrlichiosis agent.

* Corresponding author. Present address: Department of Veterinary Pathobiology, The University of Queensland, St. Lucia, QLD, Australia. Phone: 61 7 3365 3185. Fax: 61 7 3365 1355. E-mail: ghreubel{at}mailbox.uq.edu.au.

Journal of Clinical Microbiology, July 1998, p. 2131-2134, Vol. 36, No. 7
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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