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Journal of Clinical Microbiology, October 1999, p. 3235-3238, Vol. 37, No. 10
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
Slime Production and Expression of the
Slime-Associated Antigen by Staphylococcal Clinical Isolates
M. G.
Ammendolia,1
R.
Di
Rosa,2
L.
Montanaro,3
C. R.
Arciola,3 and
L.
Baldassarri1,*
Laboratorio di Ultrastrutture, Istituto
Superiore di Sanità,1 and
Dipartimento di Medicina Clinica, University "La
Sapienza" of Rome,2 Rome, and
Laboratorio di Biocompatibilità dei Materiali da
Impianto, Istituti Ortopedici Rizzoli,
Bologna,3 Italy
Received 2 March 1999/Returned for modification 30 June
1999/Accepted 15 July 1999
The ability to produce slime and to express a slime-associated
antigen was examined in a collection of staphylococcal clinical isolates. Slime-producing strains were found among coagulase-negative staphylococci in percentages comparable to those reported in other studies; surprisingly, a high percentage of Staphylococcus
aureus strains also were able to produce this extracellular
material. In the latter case, this ability was strongly dependent on
the presence of an additional carbohydrate source in the growth medium. Expression of the slime-associated antigen appeared to be species specific and confined to the Staphylococcus epidermidis
sensu stricto isolates; its strong association with the ability of
these strains to produce thicker biofilms indicated slime-associated antigen as a possible virulence marker for S. epidermidis.
*
Corresponding author. Mailing address: Laboratorio di
Ultrastrutture, Istituto Superiore di Sanità, Viale Regina Elena,
299-00161 Rome, Italy. Phone: 39/06.4990.2092. Fax: 39/06.4938.7140.
E-mail: lucilla.baldassarri{at}iss.it.
Journal of Clinical Microbiology, October 1999, p. 3235-3238, Vol. 37, No. 10
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
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