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Journal of Clinical Microbiology, December 1999, p. 4131-4134, Vol. 37, No. 12
Department of Bacteriology and Pathology,
Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, Japan
Received 1 March 1999/Returned for modification 26 June
1999/Accepted 21 August 1999
Streptococcus pyogenes isolates obtained in 1981 to
1997 from patients and healthy subjects were characterized by
pulsed-field gel electrophoresis (PFGE) patterns, biotyping, and the
presence of spe genes encoding streptococcal pyrogenic
exotoxins. Changes in the profiles were shown in the serotype M1/T1
isolates from pharyngitis over this period, but not in serotype M3/T3
isolates. The characteristics of isolates from patients with toxic
shock-like syndrome (TSLS) were comparable to those of the other
isolates, including those from healthy subjects. This finding suggests
that further phenotypic and molecular characterization, such as
investigating the genomic difference represented by the pathogenicity
island, of isolates with apparently the same profiles would be
necessary to determine the etiology of diseases caused by S. pyogenes, including TSLS.
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
Characteristics of Streptococcus
pyogenes Serotype M1 and M3 Isolates from Patients in Japan from
1981 to 1997
*
Corresponding author. Present address: Department of
Veterinary Microbiology, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan. Phone: 81-857-31-5430. Fax:
81-857-31-5430. E-mail: molamolatm{at}aol.com.
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