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Journal of Clinical Microbiology, December 1999, p. 4142-4144, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Seroepidemiology of Human Group C Rotavirus in South Africa

A. D. Steele1,* and V. L. A. James2

MRC/Medunsa Diarrhoeal Pathogens Research Unit, Medical University of Southern Africa, Pretoria, South Africa,1 and Public Health Laboratory, Southampton General Hospital, Southampton, United Kingdom2

Received 16 February 1999/Returned for modification 20 April 1999/Accepted 9 August 1999

Sera from three separate healthy population cohorts were used to determine the incidence of group C rotavirus infections in 1,356 South Africans. Using an enzyme-linked immunosorbent assay based on a recombinant group C rotavirus VP6 protein, the total percent positivity was found to be 34.4% (range, 33 to 38%), with almost half of the population infected after the age of 20 years.

* Corresponding author. Mailing address: MRC/Medunsa Diarrhoeal Pathogens Research Unit, P.O. Box 173, Medunsa 0204, Pretoria, South Africa. Phone: (27 12) 521-4117. Fax: (27 12) 521 5794. E-mail: adsteele{at}medunsa.ac.za.

Journal of Clinical Microbiology, December 1999, p. 4142-4144, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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