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Journal of Clinical Microbiology, December 1999, p. 4174-4176, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Rare Incidence of Interspousal Transmission of Helicobacter pylori in Asymptomatic Individuals in Japan

Junko Suzuki,1 Hiroe Muraoka,2 Intetsu Kobayasi,2 Toshiro Fujita,1 and Tetsuya Mine1,*

Department of Internal Medicine IV, University of Tokyo School of Medicine, Tokyo 112-8688,1 and Mitsubishi Kagaku Bio-Clinical Laboratories, Inc., Tokyo 174-00562, Japan

Received 8 March 1999/Returned for modification 14 July 1999/Accepted 7 September 1999

PCR-restriction fragment length polymorphism electrophoretic patterns of amplified ureB and ureC of Helicobacter pylori were compared between spouses after digestion with restriction endonucleases. Twenty of 21 couples, both members of which were positive for H. pylori, showed ureB and ureC patterns that differed between spouses. We concluded that in Japan, interspousal transmission of H. pylori occurs rarely.

* Corresponding author. Mailing address: Department of Internal Medicine IV, University of Tokyo School of Medicine, 3-28-6 Mejirodai, Bunkyo-ku, Tokyo 112-8688, Japan. Phone: 81-3-3943-1151. Fax: 81-3-3943-8644. E-mail: mine-tky{at}umin.ac.jp.

Journal of Clinical Microbiology, December 1999, p. 4174-4176, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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