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Journal of Clinical Microbiology, December 1999, p. 4194-4197, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Characterization of Blood Culture Isolates of Streptococcus dysgalactiae subsp. equisimilis Possessing Lancefield's Group A Antigen

Claudia M. Brandt,1,* Gerhard Haase,1 Norbert Schnitzler,1 Reinhard Zbinden,2 and Rudolf Lütticken1

Institute of Medical Microbiology and National Reference Center for Streptococci, University Hospital RWTH Aachen, Aachen, Germany,1 and Department of Medical Microbiology, University of Zürich, Zürich, Switzerland2

Received 6 July 1999/Accepted 23 August 1999

For three human blood culture isolates of beta-hemolytic streptococci with Lancefield's serogroup A antigen, phylogenetic analysis of the 16S rRNA genes confirmed biochemical identification as Streptococcus dysgalactiae subsp. equisimilis. Genes encoding M or M-like proteins, which are considered to be major virulence determinants in streptococci, were detected in all of these strains. Our data clearly demonstrate that for beta-hemolytic streptococci, the species assignment should not be based on the results of serogrouping alone.

* Corresponding author. Mailing address: Institute of Medical Microbiology, National Reference Center for Streptococci, University Hospital RWTH Aachen, Pauwelsstraße 30, D-52074 Aachen, Germany. Phone: 49-241-8089512. Fax: 49-241-8888483. E-mail: rluetticken{at}post.klinikum.rwth-aachen.de.

Journal of Clinical Microbiology, December 1999, p. 4194-4197, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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