JCM Figure table search 04
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Maslow, J. N.
Right arrow Articles by Holland, S. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Maslow, J. N.
Right arrow Articles by Holland, S. M.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, February 1999, p. 445-446, Vol. 37, No. 2
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Hemolysin as a Virulence Factor for Systemic Infection with Isolates of Mycobacterium avium Complex

Joel N. Maslow,1,* David Dawson,2 Elizabeth A. Carlin,1 and Steven M. Holland3

Infectious Diseases Section, Medical Service, VA Medical Center, and Department of Medicine, Boston University School of Medicine, Boston, Massachusetts1; Laboratory of Microbiology and Pathology, Queensland Health, Brisbane, Australia2; and Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland3

Received 28 May 1998/Returned for modification 7 July 1998/Accepted 9 November 1998

Isolates of the Mycobacterium avium complex were examined for hemolysin expression. Only invasive isolates of M. avium were observed to be hemolytic (P < 0.001), with activity the greatest for isolates of serovars 4 and 8. Thus, M. avium hemolysin appears to represent a virulence factor necessary for invasive disease.

* Corresponding author. Mailing address: Research Service (151), VA Medical Center, 150 South Huntington Ave., Boston, MA 02130. Phone: (617) 232-9500, ext. 5576. Fax: (617) 278-4540. E-mail: maslow.joel_n.md{at}boston.va.gov.

Journal of Clinical Microbiology, February 1999, p. 445-446, Vol. 37, No. 2
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 1999 by the American Society for Microbiology. All rights reserved.