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Journal of Clinical Microbiology, March 1999, p. 792-795, Vol. 37, No. 3
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Evaluation of the Ultrasensitive Roche Amplicor HIV-1 Monitor Assay for Quantitation of Human Immunodeficiency Virus Type 1 RNA

Maria Erali1 and David R. Hillyard1,2,*

ARUP Institute for Clinical and Experimental Pathology,1 and the Department of Pathology, University of Utah Health Sciences Center,2 Salt Lake City, Utah 84108

Received 21 July 1998/Returned for modification 28 September 1998/Accepted 8 December 1998

The ultrasensitive Amplicor HIV-1 Monitor test (Roche Diagnostic Systems) was evaluated for precision, linearity, and sensitivity and was compared to the standard Amplicor assay. The ultrasensitive assay reliably quantified samples in the range from 50 to 50,000 human immunodeficiency virus type 1 RNA copies/ml with acceptable correlation with the standard Amplicor test.

* Corresponding author. Mailing address: ARUP Laboratories, 500 Chipeta Way, Salt Lake City, UT 84108. Phone: (801) 583-2787, ext. 2202. Fax: (801) 584-5207. E-mail: hillyadr{at}arup-lab.com.

Journal of Clinical Microbiology, March 1999, p. 792-795, Vol. 37, No. 3
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1999 by the American Society for Microbiology. All rights reserved.