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Journal of Clinical Microbiology, March 1999, p. 844-847, Vol. 37, No. 3
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Use of Restriction Fragment Analysis and Sequencing of a Serotype-Specific Region To Type Adenovirus Isolates

Quan-Gen Li,1,2,* Anna Henningsson,1 Per Juto,1 Fredrik Elgh,1,3 and Göran Wadell1

Department of Virology, Umeå University,1 and Department of Microbiology, Division of NBC Defence, Defence Research Establishment,3 Umeå, Sweden, and Institute of Infectious Diseases, Beijing, China2

Received 8 June 1998/Returned for modification 30 September 1998/Accepted 9 December 1998

Restriction fragment analysis and sequencing of a serotype-specific region were used to type 12 and 2 clinical isolates, respectively. Both molecular methods produced clear-cut results that completely correlated with that of the neutralization test.

* Corresponding author. Mailing address: Feng Tai Road 26, Building 5-1-9, Beijing 100039, China. Phone and fax: 86-10-63845559.

Journal of Clinical Microbiology, March 1999, p. 844-847, Vol. 37, No. 3
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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