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Journal of Clinical Microbiology, May 1999, p. 1415-1418, Vol. 37, No. 5
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Clinical and Financial Benefits of Rapid Bacterial Identification and Antimicrobial Susceptibility Testing

Joan Barenfanger,1,* Cheryl Drake,1 and Gail Kacich2

Laboratory Medicine1 and Clinical Data Management,2 Memorial Medical Center, Springfield, Illinois 62781

Received 30 November 1998/Returned for modification 12 January 1999/Accepted 6 February 1999

To assess the expected clinical and financial benefits of rapid reporting of microbiology results, we compared patients whose cultured samples were processed in the normal manner to patients whose samples were processed more rapidly due to a minor change in work flow. For the samples tested in the rapid-reporting time period, the vast majority of bacterial identification and antimicrobial susceptibility testing (AST) results were verified with the Vitek system on the same day that they were available. This time period was called rapid AST (RAST). For RAST, a technologist on the evening shift verified the data that became available during that shift. For the control time period, cultures were processed in the normal manner (normal AST [NAST]), which did not include evening-shift verification. For NAST, the results for approximately half of the cultures were verified on the first day that the result was available. The average turnaround time for the reporting of AST results was 39.2 h for RAST and 44.4 h for NAST (5.2 h faster for RAST [P = 0.001]). Subsequently, physicians were able to initiate appropriate antimicrobial therapy sooner for patients whose samples were tested as part of RAST (P = 0.006). The mortality rates were 7.9 and 9.6% for patients whose samples were tested as part of RAST and NAST, respectively (P = 0.45). The average length of stay was 10.7 days per patient for RAST and 12.6 days for NAST, a difference of 2.0 days less for RAST (P = 0.006). The average variable cost was $4,927 per patient for RAST and $6,677 for NAST, a difference of $1,750 less per patient for RAST (P = 0.001). This results in over $4 million in savings in variable costs per year in our hospital.

* Corresponding author. Mailing address: Laboratory Medicine, Memorial Medical Center, 701 N. First St., Springfield, IL 62781. Phone: (217) 788-3000. Fax: (217) 788-5577. E-mail: barenfanger.joan{at}mhsil.com.

Journal of Clinical Microbiology, May 1999, p. 1415-1418, Vol. 37, No. 5
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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