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Journal of Clinical Microbiology, May 1999, p. 1632-1633, Vol. 37, No. 5
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Ability of a Rapid Serology Test To Detect Seroconversion to Herpes Simplex Virus Type 2 Glycoprotein G Soon after Infection

Rhoda L. Ashley,1,* Marie Eagleton,2 and Natasha Pfeiffer1

Department of Laboratory Medicine, University of Washington, Seattle, Washington,1 and Diagnology Ltd., Belfast, Northern Ireland2

Received 17 September 1998/Returned for modification 7 December 1998/Accepted 5 February 1999

Sera (n = 188) from 29 patients with first-episode genital herpes simplex virus type 2 (HSV-2) infections were tested by POCkit-HSV-2 and Western blot (WB) to determine the speed of seroconversion. The median time to detection of HSV-2 antibody was 13 days (range, 3 to 102 days) by the POCkit-HSV-2 test versus 13 days (range, 2 to 58 days) for WB.

* Corresponding author. Mailing address: Virology Office, Room G-815, Children's Hospital and Regional Medical Center, CH-82, 4800 Sand Point Way, NE, Seattle, WA 98105. Phone: (206) 526-2117. Fax: (206) 527-3885. E-mail: rashle{at}chmc.org.

Journal of Clinical Microbiology, May 1999, p. 1632-1633, Vol. 37, No. 5
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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