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Journal of Clinical Microbiology, June 1999, p. 2051-2052, Vol. 37, No. 6
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Southern Extension of the Range of Human Babesiosis in the Eastern United States

Eugene S. Eskow,1 Peter J. Krause,2,* Andrew Spielman,3 Kathy Freeman,2 and Jaber Aslanzadeh2

403 Highway 202, Flemington, New Jersey,1 The University of Connecticut, Farmington, Connecticut,2 and the Harvard School of Public Health, Boston, Massachusetts3

Received 19 January 1999/Returned for modification 2 February 1999/Accepted 1 March 1999

We sought evidence of babesiosis in three residents of New Jersey who were suspected of local acquisition of Babesia microti infection. We tested serial blood samples from these residents for B. microti antibodies and amplifiable DNA by using immunofluorescent antibody and PCR techniques. All three residents experienced symptoms suggestive of acute babesiosis. The sera of each of the patients reacted against babesial antigen at a titer fourfold or higher in sequentially collected blood samples. PCR-amplifiable DNA, characteristic of B. microti, was detected in their blood. These data suggest that human B. microti infections were acquired recently in New Jersey, extending the range of this piroplasmosis in the northeastern United States.

* Corresponding author. Present address: Connecticut Children's Medical Center, 282 Washington St., Hartford, CT 06106. Phone: (860) 545-9490. Fax: (860) 545-9371. E-mail: PKRAUSE{at}CCMCKIDS.org.

Journal of Clinical Microbiology, June 1999, p. 2051-2052, Vol. 37, No. 6
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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