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Journal of Clinical Microbiology, June 1999, p. 2061-2063, Vol. 37, No. 6
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Detection of Antibodies to Hepatitis C Virus in Dried Blood Spot Samples from Mothers and Their Offspring in Lahore, Pakistan

S. P. Parker,1,* H. I. Khan,2 and W. D. Cubitt1

Virology Department, Camelia Botnar Laboratories, Great Ormond Street Hospital for Children, London WC1N 3JH, United Kingdom,1 and Department of Paediatrics, King Edward Medical College & Mayo Hospital, Lahore, Pakistan2

Received 2 November 1998/Returned for modification 25 January 1999/Accepted 15 March 1999

Dried blood spot samples from mothers and their offspring attending the obstetric and pediatric departments of two hospitals in Lahore, Pakistan, were tested for antibodies to hepatitis C virus (HCV). The seroprevalence of HCV in the women was 6.7% (95% confidence interval [CI], 4.3 to 9.1), and that in the children was 1.3% (95% CI, 0.34 to 2.26). Four anti-HCV immunoglobulin G (IgG)-positive children had mothers that were anti-HCV IgG negative, which suggested that their infection was community acquired.

* Corresponding author. Mailing address: Virology Department, Camelia Botnar Laboratories, Great Ormond Street Hospital for Children, London WC1N 3JH, United Kingdom. Phone: 0171 405 9200, ext. 2420. Fax: 0171 829 8639. E-mail simon.parker{at}GOSH-TR.NTHAMES.NHS.UK.

Journal of Clinical Microbiology, June 1999, p. 2061-2063, Vol. 37, No. 6
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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