This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Menéndez, C.
Right arrow Articles by Saiz, J.-C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Menéndez, C.
Right arrow Articles by Saiz, J.-C.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, July 1999, p. 2333-2336, Vol. 37, No. 7
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Molecular Evidence of Mother-to-Infant Transmission of Hepatitis G Virus among Women without Known Risk Factors for Parenteral Infections

Clara Menéndez,1,2 José-María Sánchez-Tapias,1 Pedro-Luis Alonso,2 Mireia Giménez-Barcons,1 Elizeus Kahigwa,3 John-Jairo Aponte,2 Hassan Mshinda,4 Margarita-María Navia,5 María-Teresa Jiménez de Anta,5 Juan Rodés,1 and Juan-Carlos Saiz1,*

Liver Unit, Department of Medicine,1 and Unidad de Epidemiologia y Bioestadistica,2 Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), and Department of Microbiology,5 Hospital Clinic, Barcelona, Spain, and St. Francis Designated District Hospital3 and Ifakara Health Research and Development Centre,4 Ifakara, Tanzania

Received 26 October 1998/Returned for modification 4 February 1999/Accepted 15 March 1999

Hepatitis G virus (HGV) RNA was detected in 18 of 133 pregnant women from Tanzania without known risk factors for HGV infection and in 7 of 18 children born to HGV RNA-positive mothers. Molecular evidence of mother-to-infant transmission was obtained only for three of seven children. HGV RNA was also detected in 4 of 42 children born to non-HGV-infected women. Thus, mechanisms other than materno-filial may play an important role in HGV transmission during early childhood.

* Corresponding author. Mailing address: Liver Unit, Department of Medicine, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic, Barcelona, Spain. Phone: 34-93-227-54-00. Fax: 34-93-451-52-72. E-mail: JCSAIZ{at}MEDICINA.UB.ES.

Journal of Clinical Microbiology, July 1999, p. 2333-2336, Vol. 37, No. 7
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Simmonds, P. (2004). Genetic diversity and evolution of hepatitis C virus - 15 years on. J. Gen. Virol. 85: 3173-3188 [Abstract] [Full Text]  
  • Simmonds, P. (2001). 2000 Fleming Lecture. The origin and evolution of hepatitis viruses in humans. J. Gen. Virol. 82: 693-712 [Abstract] [Full Text]  
  • Handa, A., Brown, K. E. (2000). GB virus C/hepatitis G virus replicates in human haematopoietic cells and vascular endothelial cells. J. Gen. Virol. 81: 2461-2469 [Abstract] [Full Text]  
  • Chen, M., Fischler, B., Hultgren, C., Halasz, R., Nemeth, A., Sällberg, M. (1999). Analysis of GB Virus C Markers in Families Over Three Generations. J. Clin. Microbiol. 37: 4153-4155 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»