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Journal of Clinical Microbiology, August 1999, p. 2703-2705, Vol. 37, No. 8
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

TT Virus Infection Is Widespread in the General Populations from Different Geographic Regions

Kenji Abe,1,* Tomoko Inami,1 Kazue Asano,2 Chiaki Miyoshi,3 Naohiko Masaki,4 Shigeki Hayashi,4 Ko-ichi Ishikawa,5 Yutaka Takebe,5 Khin Maung Win,6 Abdel Rahman El-Zayadi,7 Kwang-Hyub Han,8 and David Y. Zhang9

Department of Pathology1 and AIDS Research Center,5 National Institute of Infectious Diseases, and Bureau of International Cooperation3 and Division of Gastroenterology,4 International Medical Center of Japan, Tokyo, and Department of Pediatrics, Seirei Hamamatsu General Hospital, Shizuoka,2 Japan; Department of Hepatology, Yangon General Hospital, Yangon, Myanmar6; Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt7; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea8; and Department of Pathology, The Mount Sinai Medical Center of the City University of New York, New York, New York9

Received 22 February 1999/Returned for modification 28 April 1999/Accepted 18 May 1999

By PCR screening, we found an extremely high prevalence of TT virus (TTV) in the general populations from different geographic regions. This suggests that TTV may be a common DNA virus with no clear disease association in humans. TTV genotyping by phylogenetic analysis was also performed.

* Corresponding author. Mailing address: Department of Pathology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo 162-8640, Japan. Phone: (81) 3-5285-1111, ext. 2624. Fax: (81) 3-5285-1189 or (81) 3-5285-1150. E-mail: kenjiabe{at}nih.go.jp.

Journal of Clinical Microbiology, August 1999, p. 2703-2705, Vol. 37, No. 8
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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