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Journal of Clinical Microbiology, August 1999, p. 2729-2733, Vol. 37, No. 8
Microbiology Service, Clinical Pathology
Department, National Institutes of Health, Bethesda, Maryland
20892,1 and Department of Infectious
Diseases, Veterans Affairs Medical Center, Washington, D.C.
204222
Received 16 December 1998/Returned for modification 7 February
1999/Accepted 21 April 1999
An unusual Helicobacter sp. was isolated from the blood
of a human immunodeficiency virus (HIV)-infected patient. This organism had spiral morphology, with single amphitrichous flagella, and was
negative for hippurate hydrolysis, production of urease, and reduction
of nitrate. 16S rRNA gene sequence analysis verified that the isolate
was a species of Helicobacter, most closely related to an
undescribed Helicobacter-like isolate from Vancouver,
British Columbia, Canada, and to Helicobacter westmeadii, a
recently described species from Australia. Both organisms had also been
isolated from the blood of HIV-infected patients. These blood isolates, along with Helicobacter cinaedi, form a cluster of closely
related Helicobacter spp. that may represent an emerging
group of pathogens in immunocompromised patients.
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
An Uncommon Helicobacter Isolate from
Blood: Evidence of a Group of Helicobacter spp. Pathogenic
in AIDS Patients
*
Corresponding author. Mailing address: Microbiology
Service, Clinical Pathology Department, Building 10, Room 2C-385, 9000 Rockville Pike, Bethesda, MD 20892. Phone: (301) 496-4433. Fax: (301)
402-1886. E-mail: vgill{at}nih.gov.
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