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Journal of Clinical Microbiology, January 2000, p. 393-394, Vol. 38, No. 1
0095-1137/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Evaluation of a Combination Rapid Immunoassay for Detection of Giardia and Cryptosporidium Antigens

Raymond Chan,1,* Jing Chen,1 Mary K. York,2 Norman Setijono,2 Raymond L. Kaplan,3 Fitzroy Graham,4 and Herbert B. Tanowitz4

Genzyme Diagnostics, San Carlos,1 and University of California, San Francisco,2 California; SmithKline Beecham Clinical Laboratories, Tucker, Georgia3; and Albert Einstein College of Medicine, Bronx, New York4

Received 29 April 1999/Returned for modification 24 June 1999/Accepted 8 October 1999

A combination cassette format nonenzymatic rapid immunoassay for detection of Giardia and Cryptosporidium antigens was evaluated by using 556 patient stool specimens from three clinical laboratories. This assay (Genzyme Diagnostics Contrast Giardia/Cryptosporidium), which can be used with fresh or formalin-fixed specimens, had unadjusted sensitivities and specificities of 96.1 and 98.5% for Giardia and 100 and 98.7% for Cryptosporidium, respectively, in this study.

* Corresponding author. Mailing address: Genzyme Diagnostics, 1531 Industrial Rd., San Carlos, CA 94070. Phone: (650) 594-0513. Fax: (650) 594-0571. E-mail: raymond.chan{at}genzyme.edu.

Journal of Clinical Microbiology, January 2000, p. 393-394, Vol. 38, No. 1
0095-1137/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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