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Journal of Clinical Microbiology, January 2000, p. 408-411, Vol. 38, No. 1
0095-1137/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Additional Human Papillomavirus Types Detected by the Hybrid Capture Tube Test among Samples from Women with Cytological and Colposcopical Atypia

József Kónya,1,* György Veress,1 Attila Juhász,1 Krisztina Szarka,1 Tamás Sápy,2 Zoltán Hernádi,2 and Lajos Gergely1

Department of Microbiology1 and Department of Obstetrics and Gynecology,2 University Medical School of Debrecen, Debrecen, Hungary

Received 3 May 1999/Returned for modification 21 July 1999/Accepted 8 October 1999

The type specificity of the human papillomavirus (HPV) Hybrid Capture Tube (HCT) test was evaluated by using typing with PCR (MY09-MY11)-restriction fragment length polymorphism (RFLP) and sequencing. All samples HCT test positive for only low-risk HPV (n = 15) or only high-risk HPV (n = 102) were confirmed, whereas 9 of 12 HCT test double-positive samples contained only high-risk HPV types as determined by PCR-RFLP. Several high-risk HPV types (HPV-53, -58, -62, -66, -CP8304, and -MM4) not included in the HCT test were indeed detected, indicating a broader detection range with retained distinction between low-risk and high-risk HPV types.

* Corresponding author. Mailing address: Department of Microbiology, University Medical School of Debrecen, P.O. Box 17, H-4012 Debrecen, Hungary. Phone and Fax: 36 52 417-565. E-mail: konya{at}mibio.dote.hu.

Journal of Clinical Microbiology, January 2000, p. 408-411, Vol. 38, No. 1
0095-1137/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Borbely, A A, Murvai, M, Szarka, K, Konya, J, Gergely, L, Hernadi, Z, Veress, G (2007). Survivin promoter polymorphism and cervical carcinogenesis. J. Clin. Pathol. 60: 303-306 [Abstract] [Full Text]  
  • Szladek, G, Juhasz, A, Kardos, G, Szoke, K, Major, T, Sziklai, I, Tar, I, Marton, I, Konya, J, Gergely, L, Szarka, K (2005). High co-prevalence of genogroup 1 TT virus and human papillomavirus is associated with poor clinical outcome of laryngeal carcinoma. J. Clin. Pathol. 58: 402-405 [Abstract] [Full Text]  
  • Iftner, T., Villa, L. L. (2003). Chapter 12: Human Papillomavirus Technologies. J Natl Cancer Inst Monogr 2003: 80-88 [Abstract] [Full Text]  


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