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Journal of Clinical Microbiology, January 2000, p. 450-452, Vol. 38, No. 1
0095-1137/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
A Clonal Subpopulation of Leptospira
interrogans Sensu Stricto Is the Major Cause of Leptospirosis
Outbreaks in Brazil
M. M.
Pereira,1,*
M. G. S.
Matsuo,2
A. R.
Bauab,2
S. A.
Vasconcelos,3
Z. M.
Moraes,3
G.
Baranton,4 and
I.
Saint Girons4
National Reference Center for Leptospirosis,
Instituto Oswaldo Cruz, Rio de Janeiro,1 and
Center for Zoonosis Control2 and
University of São Paulo,3
São Paulo, Brazil, and Unité de
Bactériologie Moléculaire et Médicale, Institut
Pasteur, 75724 Paris, France4
Received 28 July 1999/Accepted 22 September 1999
Leptospira is a highly diverse genus comprising many
species and serogroups in Brazil as well as all over the world.
However, a study by arbitrarily primed PCR of 44 leptospiral strains
isolated from humans during three different outbreaks in Brazilian
urban centers reveals that 43 of 44 isolates exhibit very similar
fingerprints. Analysis of these isolates indicates that they belong to
a clonal subpopulation of Leptospira interrogans sensu stricto.
*
Corresponding author. Mailing address: Department of
Bacteriology, Oswaldo Cruz Institute/FIOCRUZ, Avenida Brasil, 4365, 21045-900. Rio de Janeiro, Brazil. Phone: 55-21-270-3545. Fax:
55-21-590-3545. E-mail:
mpereira{at}gene.dbbm.fiocruz.br.
Journal of Clinical Microbiology, January 2000, p. 450-452, Vol. 38, No. 1
0095-1137/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
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