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Journal of Clinical Microbiology, November 2000, p. 4277-4279, Vol. 38, No. 11
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Detection of Hepatitis G Virus (HGV) RNA and Antibodies to the HGV Envelope Protein E2 in a Cohort of Hemodialysis Patients

T. Pérez-Gracia,1 F. Galán,1 J. A. Girón-González,2,* A. Lozano,3 B. Benavides,3 E. Fernández,3 and M. Rodríguez-Iglesias1

Servicio de Microbiología,1 and Servicio de Nefrología,3 Hospital Universitario Puerto Real, and Servicio de Medicina Interna, Hospital Universitario Puerta del Mar,2 Cádiz, Spain

Received 22 February 2000/Returned for modification 19 May 2000/Accepted 14 July 2000

An analysis of the evolution of hepatitis G virus (HGV) infection markers was performed for a cohort of 58 hemodialyzed patients. During follow-up (4.88 ± 0.42 years), a group of these patients cleared their antibodies against the envelope protein E2 with (4 of 29 cases; 13.8%) or without (9 of 29 cases; 31%) the reappearance of viremia. This finding implies a temporally limited protection in patients previously infected with HGV.

* Corresponding author. Mailing address: Servicio de Medicina Interna, Hospital Universitario Puerta del Mar, avda Ana de Viya 3, 11009 Cádiz, Spain. Phone and fax: 34 956 242347. E-mail: epgei{at}comcadiz.es.

Journal of Clinical Microbiology, November 2000, p. 4277-4279, Vol. 38, No. 11
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.




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