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Journal of Clinical Microbiology, February 2000, p. 866-869, Vol. 38, No. 2
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Heterogeneous Vancomycin Resistance in Methicillin-Resistant Staphylococcus aureus Strains Isolated in a Large Italian Hospital

A. Marchese,* G. Balistreri, E. Tonoli, E. A. Debbia, and G. C. Schito

Institute of Microbiology, University of Genoa, Genoa, Italy

Received 23 June 1999/Returned for modification 30 August 1999/Accepted 4 November 1999

Of 179 methicillin-resistant Staphylococcus aureus strains isolated from 1997 to 1998, two strains (1.1%) gave subclones for which the vancomycin MICs were 8 mg/liter. Pulsed-field gel electrophoresis showed identical restriction patterns for both isolates, suggesting transfer of a single clone between two different patients.


* Corresponding author. Mailing address: Institute of Microbiology, Largo R. Benzi, 10, 16132 Genoa, Genoa, Italy. Phone: 39-010-3537655. Fax: 39-010-504837. E-mail: genmicr{at}unige.it.


Journal of Clinical Microbiology, February 2000, p. 866-869, Vol. 38, No. 2
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.



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