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Journal of Clinical Microbiology, February 2000, p. 866-869, Vol. 38, No. 2
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Heterogeneous Vancomycin Resistance in Methicillin-Resistant
Staphylococcus aureus Strains Isolated in a Large
Italian Hospital
A.
Marchese,*
G.
Balistreri,
E.
Tonoli,
E. A.
Debbia, and
G. C.
Schito
Institute of Microbiology, University of
Genoa, Genoa, Italy
Received 23 June 1999/Returned for modification 30 August
1999/Accepted 4 November 1999
Of 179 methicillin-resistant Staphylococcus aureus
strains isolated from 1997 to 1998, two strains (1.1%) gave subclones
for which the vancomycin MICs were 8 mg/liter. Pulsed-field gel
electrophoresis showed identical restriction patterns for both
isolates, suggesting transfer of a single clone between two different patients.
*
Corresponding author. Mailing address: Institute of
Microbiology, Largo R. Benzi, 10, 16132 Genoa, Genoa, Italy. Phone:
39-010-3537655. Fax: 39-010-504837. E-mail:
genmicr{at}unige.it.
Journal of Clinical Microbiology, February 2000, p. 866-869, Vol. 38, No. 2
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
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